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Antimicrobial resistance profiles of Mycobacterium tuberculosis

Antimicrobial resistance profiles of Mycobacterium tuberculosis

The information is based on Mycobacterium tuberculosis strains isolated / received by the laboratory during the designated year.

Year Total isolates tested Susceptible to H, R, E and S Susceptible to H, R, E and Z Any resistance Mono resistance MDR-TB (excluding XDR-TB) XDR-TB
H R E S Z H R E S Z HR only HRE only HRS only HRZ only HRES only HREZ only Others
2006 6542 5818 370 137 79 528 139 19 3 323 18 3 22 31 20 15
2007 6641 5881 368 102 44 572 139 18 3 363 17 2 22 5 14 16
2008 6789 6004 355 127 73 576 144 18 4 395 25 1 11 7 37 15
2009 6465 5608 428 174 85 643 147 17 5 400 28 5 43 29 28 18
2010 6021 5268 359 119 53 600 124 7 0 383 18 1 35 17 20 17
2011 5779 5114 304 74 19 496 130 20 3 335 11 1 20 4 10 6
2012 6096 5281 359 121 62 647 129 13 13 424 2 0 45 3 38 14
2013 5742 4982 344 149 101 582 91 17 10 371 12 14 32 11 27 18
2014 4564 3921 283 73 60 489 110 8 12 337 4 4 30 8 8 8
2015 3869 3366 251 64 36 386 92 5 5 239 10 1 16 9 16 5
2016 4077 3571 276 47 26 385 99 7 3 216 4 0 17 6 7 2
2017 4001 3479 269 47 34 394 103 10 5 238 2 2 13 8 12 0
2018 4092 3623 230 51 20 341 101 10 1 227 12 0 13 1 13 1
2019 3794 3353 234 35 19 320 103 2 2 203 5 0 10 3 15 0
2020 3383 3011 187 23 25 265 88 5 4 176 1 0 4 5 8 0
2021 3484 3121 176 28 14 261 77 8 2 177 6 1 7 0 6 0
2022 3054 2696 183 30 11 264 73 6 2 167 9 0 8 0 7 0
2023# 3218 1635 1255 201 30 27 155 23 115 8 9 89 19 5 1 2 0 1 3 8 1

Remarks:
Multiple strains may have been isolated from the same patient.
#Pyrazinamide (Z) has replaced streptomycin (S) in 1st line MTB drug susceptibility testing since August 2023. The total number of MTB isolates with DST performed on HRES and HREZ as 1st line drugs are 1867 and 1351 respectively. 

Abbreviations:
H = isonizaid, R = rifampicin, E = ethambutol, S = streptomycin, Z = pyrazinamide
MDR-TB = multidrug-resistant tuberculosis, XDR-TB = extensively drug-resistant tuberculosis